For laboratory research use only. Every lot independently tested; certificates published by lot.

MT1 research: overview and resources

What MT1 research material is, how it is characterized, and where to find every specification, method, lot record and reference MT1 Peptide Co. publishes about it.

Published October 2, 2026. Updated November 12, 2026. By the MT1 Peptide Co. Research Team.

What is MT1?

The MT1 peptide, Melanotan I, is α-melanocyte-stimulating hormone with two deliberate changes: norleucine at position 4 and D-phenylalanine at position 7. The first removes a methionine that oxidizes easily; the second resists enzymatic cleavage and strengthens binding at the melanocortin 1 receptor. The 13-residue chain keeps α-MSH's acetylated N-terminus and amidated C-terminus, giving C78H111N21O19 and 1646.85 g/mol.

MT1 Peptide Co. lists MT1 in 10 mg vials at $29.99 through Klow.bio. Lot KB-34289 tested at 97.55% by HPLC at ILS Laboratories, with Melanotan I identity confirmed against a reference standard.

MT1 is a linear peptide and a different compound from Melanotan II (MT2), which is a shorter, cyclic analog. The two have different formulas and molecular weights (1646.85 vs 1024.18 g/mol).

What is MT1 research material?

MT1 research material is Melanotan I supplied for laboratory research (C78H111N21O19, 1646.85 g/mol) in lyophilized powder form, sold by lot. Each lot's identity, purity and net content are documented by an independent laboratory in a published certificate of analysis.

How is MT1 characterized?

Three questions are answered for every lot, each by a different method:

  • Is it the right compound? The laboratory runs the sample and a reference standard of the named compound under the same HPLC conditions; identity is confirmed when the main peak elutes at the reference standard’s retention time.
  • How much of the sample is that compound? HPLC-UV reports the main peak's share of detected peak area. Current lots: 97.55%.
  • How much peptide is in the vial? Net content is measured directly.

Endotoxin (LAL) and microbial DNA (PCR) results are added where those tests are run.

What has not been established

A certificate of analysis describes the specific sample tested on its test date. It does not establish stability afterward, sequence order beyond what mass confirmation shows, results for other lots, or suitability for any particular purpose.

MT1 at a glance

Product
Melanotan I
Type
Synthetic linear α-MSH analog (13 residues), 13 residues
Also known as
MT1, MT-I, [Nle4, D-Phe7]-α-MSH, NDP-α-MSH
Receptor design
Melanocortin 1 receptor (MC1R)
Molecular formula
C78H111N21O19
Molecular weight
1646.85 g/mol (average)
Form
Lyophilized powder
Vial sizes
10 mg
Purity, current lots
97.55% (HPLC-UV)
Purity specification
≥95%
Identity
Confirmed by HPLC retention-time match on every lot
Testing laboratory
ILS Laboratories (independent)
Current lot
KB-34289, reported Sep 12, 2026
Operated by
Klow Labs LLC, Chicago, IL
Where to order
klow.bio

Research references

Published sources

  1. PubChem: Melanotan I. National Library of Medicine, NIH. pubchem.ncbi.nlm.nih.gov/compound/16164658
  2. NCBI Gene: MC1R (melanocortin 1 receptor). National Center for Biotechnology Information, NIH. www.ncbi.nlm.nih.gov/gene/4157
  3. NCBI Gene: POMC (proopiomelanocortin, the α-MSH precursor). National Center for Biotechnology Information, NIH. www.ncbi.nlm.nih.gov/gene/5443
  4. Wilm M. Principles of electrospray ionization. Mol Cell Proteomics. 2011. PMC3134074. pmc.ncbi.nlm.nih.gov/articles/PMC3134074
  5. U.S. FDA. Q2(R2) Validation of Analytical Procedures. 2024. fda.gov
  6. U.S. FDA. Pyrogen and Endotoxins Testing: Questions and Answers. Revised 2026. fda.gov

MT1 Peptide Co. analytical documentation

Editorial scope

MT1 Peptide Co. research content covers molecular characteristics, peptide structure, analytical chemistry, purity and identity testing, certificates of analysis, lot documentation and laboratory storage and handling.

It does not cover dosing, administration instructions, protocols, personal use or medical advice.

Latest updates

All research updates

Buy MT1

10 mg vials. Current lot KB-34289 tested at 97.55% purity with identity confirmed by HPLC retention-time match against a reference standard. Current purchasing is available through Klow.bio.